Experiment / E1M0F7BW73' UTR / RNA Stability MPRA (MPRAu)

CXCL2 full-length 3′-UTR overlapping fast-UTR mutation scan

Massively parallel functional annotation of 3′ untranslated regions

A pooled library of overlapping 128-nt segments spanning the CXCL2 3′-UTR was used in BEAS-2B cells to measure the effect of spontaneous mutations in 8-nt windows on reporter steady-state mRNA. The table contains the published genome-browser track values for each window center.

Download processed table (CSV)Raw source data API documentation

Processed tables are specific to each experiment. Column names, units, measurements, and table structure are not standardized across the database. Check this experiment’s column definitions and quality-control notes before comparing or combining data.

Organism: Human
Taxonomy ID: NCBITaxon:9606
Biosample: CVCL:0168
Reference genome: GRCh37/hg19
Design focus: Region-focused
Region of interest: chr4:74962780-74963465

Perturbation & assay details

Basal / Untreated

The complete CXCL2 3′-UTR library used 205 overlapping 128-nt segments (4-nt spacing, with end padding) and a 12-nt clone index. The table is the steady-state mRNA track from that library, not a list of GWAS variants.

Processed data

50 rows per page. Click a cell to inspect its full value.

Visible columns (10 of 10)

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Page 1 · 50 rows · More results available

Filters apply to this table only. The CSV download contains the complete processed table; filtered rows are available through the API.

Column dictionary · 10 definitions

window_id: Identifier assigned to each consecutive published WIG window record.
gene: Tested gene, CXCL2.
chromosome: Chromosome containing the tested 3′-UTR.
window_center_1based: 1-based genomic coordinate reported as the center position of the 8-nt mutation window.
reference_genome: Assembly used for the track coordinates.
strand: Genomic strand of CXCL2; negative strand.
window_length_nt: Length of the mutation window described by the authors.
delta_mrna: Published median difference in steady-state reporter mRNA between mutant and wild-type clones.
neg_log10_p: Published −log10 p-value for the mutation-window comparison.
p_value: p-value reconstructed as 10^(−neg_log10_p).

Quality control

The authors removed clone indexes with mean <10 reads and excluded segments represented by fewer than 10 clones. The processed table retains all 674 finite 8-nt-window records in the published Supplementary Data 1 tracks.

Curation notes

Supplementary Data 1 reports window-center tracks rather than clone-level counts or individual mutation identities. The WIG browser position is a display interval; the table preserves the track coordinates and does not infer window endpoints.

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