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Experiment / E2ZZRSAHUEpisomal Plasmid MPRA

Scale-up Sharpr-MPRA minP track in HepG2

Genome-scale high-resolution mapping of activating and repressive nucleotides in regulatory regions

The minimal TATA promoter scale-up MPRA was assayed in HepG2 across two 244K array designs and two biological replicates. Each of 15,720 selected 295-bp regions was tiled with overlapping 145-bp reporter constructs at 5-bp offsets; this table contains the authors' inferred base-resolution minP scores.

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Processed tables are specific to each experiment. Column names, units, measurements, and table structure are not standardized across the database. Check this experiment’s column definitions and quality-control notes before comparing or combining data.

Organism
Human
Taxonomy ID
NCBITaxon:9606
Biosample
CVCL:0027
Reference genome
hg19
Design focus
Region-focused
Region of interest
Not reported / not applicable
Perturbation & assay details

Basal / Untreated; minimal TATA promoter

The scale-up library used 145-bp inserts cloned upstream of either a minimal TATA promoter (minP) or strong SV40 promoter and placed one 10-nt barcode per tile in the reporter 3-prime UTR. The published SHARPR procedure inferred scores for 59 five-base intervals and interpolated them to 295 individual nucleotide positions using variance priors of 1 and 50, conservative sign agreement, replicate averaging, and the authors' region-score maximum-absolute-value rule. This track uses the minimal TATA promoter reporter cassette. The two array designs contain complementary region sets, each region is represented by up to 31 one-barcode tiles, and the two RNA replicates for each promoter are normalized to the matching plasmid DNA pool.

Processed data

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Filters apply to this table only. The CSV download contains the complete processed table; filtered rows are available through the API.

Column dictionary · 331 definitions
region_id
Original 295-bp scale-up region identifier.
score_track
Published SHARPR score track: minP, SV40P, or combinedP.
array_design
Array design contributing the region, ScaleUpDesign1 or ScaleUpDesign2.
source_selection_cell_type
Cell type whose DNase/chromatin-state selection supplied the region; not the assayed cell type.
chromatin_state
25-state ChromHMM state used in the source region selection.
region_index
Integer region index within the source selection cell type and chromatin state.
chromosome
hg19 chromosome.
region_center
Center coordinate encoded in the original region identifier, in hg19.
region_start
0-based inclusive hg19 start of the 295-bp tiled region.
region_end
0-based exclusive hg19 end of the 295-bp tiled region.
region_length_bp
Length of the tiled region in base pairs.
tiles_available_minP
Number of scale-up tile count rows available for the minP plasmid/RNA library.
tiles_available_SV40P
Number of scale-up tile count rows available for the SV40P plasmid/RNA library.
dna_passing_tiles_minP
Number of minP tiles with original plasmid DNA count >=20.
dna_passing_tiles_SV40P
Number of SV40P tiles with original plasmid DNA count >=20.
dna_passing_tiles_any_promoter
Number of distinct tile positions with DNA count >=20 in either promoter library.
dna_count_sum_minP
Sum of original minP plasmid DNA counts across available tiles.
dna_count_sum_SV40P
Sum of original SV40P plasmid DNA counts across available tiles.
rna_count_sum_rep1_minP
Sum of raw minP reporter RNA counts across available tiles, replicate 1.
rna_count_sum_rep2_minP
Sum of raw minP reporter RNA counts across available tiles, replicate 2.
rna_count_sum_rep1_SV40P
Sum of raw SV40P reporter RNA counts across available tiles, replicate 1.
rna_count_sum_rep2_SV40P
Sum of raw SV40P reporter RNA counts across available tiles, replicate 2.
rna_nonzero_tiles_rep1_minP
Available minP tile rows with reporter RNA count >0 in replicate 1.
rna_nonzero_tiles_rep2_minP
Available minP tile rows with reporter RNA count >0 in replicate 2.
rna_nonzero_tiles_rep1_SV40P
Available SV40P tile rows with reporter RNA count >0 in replicate 1.
rna_nonzero_tiles_rep2_SV40P
Available SV40P tile rows with reporter RNA count >0 in replicate 2.
region_score
Signed SHARPR score at the nucleotide with maximum absolute score; this is the authors' region-level score definition.
max_abs_score
Absolute value of region_score.
max_score_position_0based
0-based position within the 295-bp region at which region_score occurs.
max_score_genomic_coordinate
Chromosome and 0-based coordinate of region_score, formatted chromosome:position.
mean_score
Mean SHARPR score across the 295 nucleotide positions.
min_score
Minimum SHARPR score across the 295 nucleotide positions.
max_score
Maximum SHARPR score across the 295 nucleotide positions.
n_positive_score_positions
Number of the 295 positions with score >0.
n_negative_score_positions
Number of the 295 positions with score <0.
qc_pass
TRUE when all 295 source scores are finite and the matching promoter track has at least one DNA-qualified tile; combinedP uses either promoter.
score_000
Published SHARPR regulatory activity score for base position 0 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_001
Published SHARPR regulatory activity score for base position 1 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_002
Published SHARPR regulatory activity score for base position 2 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_003
Published SHARPR regulatory activity score for base position 3 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_004
Published SHARPR regulatory activity score for base position 4 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_005
Published SHARPR regulatory activity score for base position 5 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_006
Published SHARPR regulatory activity score for base position 6 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_007
Published SHARPR regulatory activity score for base position 7 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_008
Published SHARPR regulatory activity score for base position 8 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_009
Published SHARPR regulatory activity score for base position 9 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_010
Published SHARPR regulatory activity score for base position 10 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_011
Published SHARPR regulatory activity score for base position 11 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_012
Published SHARPR regulatory activity score for base position 12 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_013
Published SHARPR regulatory activity score for base position 13 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_014
Published SHARPR regulatory activity score for base position 14 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_015
Published SHARPR regulatory activity score for base position 15 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_016
Published SHARPR regulatory activity score for base position 16 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_017
Published SHARPR regulatory activity score for base position 17 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_018
Published SHARPR regulatory activity score for base position 18 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_019
Published SHARPR regulatory activity score for base position 19 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_020
Published SHARPR regulatory activity score for base position 20 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_021
Published SHARPR regulatory activity score for base position 21 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_022
Published SHARPR regulatory activity score for base position 22 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_023
Published SHARPR regulatory activity score for base position 23 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_024
Published SHARPR regulatory activity score for base position 24 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_025
Published SHARPR regulatory activity score for base position 25 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_026
Published SHARPR regulatory activity score for base position 26 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_027
Published SHARPR regulatory activity score for base position 27 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_028
Published SHARPR regulatory activity score for base position 28 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_029
Published SHARPR regulatory activity score for base position 29 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_030
Published SHARPR regulatory activity score for base position 30 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_031
Published SHARPR regulatory activity score for base position 31 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_032
Published SHARPR regulatory activity score for base position 32 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_033
Published SHARPR regulatory activity score for base position 33 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_034
Published SHARPR regulatory activity score for base position 34 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_035
Published SHARPR regulatory activity score for base position 35 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_036
Published SHARPR regulatory activity score for base position 36 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_037
Published SHARPR regulatory activity score for base position 37 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_038
Published SHARPR regulatory activity score for base position 38 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_039
Published SHARPR regulatory activity score for base position 39 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_040
Published SHARPR regulatory activity score for base position 40 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_041
Published SHARPR regulatory activity score for base position 41 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_042
Published SHARPR regulatory activity score for base position 42 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_043
Published SHARPR regulatory activity score for base position 43 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_044
Published SHARPR regulatory activity score for base position 44 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_045
Published SHARPR regulatory activity score for base position 45 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_046
Published SHARPR regulatory activity score for base position 46 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_047
Published SHARPR regulatory activity score for base position 47 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_048
Published SHARPR regulatory activity score for base position 48 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_049
Published SHARPR regulatory activity score for base position 49 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_050
Published SHARPR regulatory activity score for base position 50 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_051
Published SHARPR regulatory activity score for base position 51 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_052
Published SHARPR regulatory activity score for base position 52 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_053
Published SHARPR regulatory activity score for base position 53 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_054
Published SHARPR regulatory activity score for base position 54 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_055
Published SHARPR regulatory activity score for base position 55 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_056
Published SHARPR regulatory activity score for base position 56 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_057
Published SHARPR regulatory activity score for base position 57 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_058
Published SHARPR regulatory activity score for base position 58 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_059
Published SHARPR regulatory activity score for base position 59 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_060
Published SHARPR regulatory activity score for base position 60 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_061
Published SHARPR regulatory activity score for base position 61 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_062
Published SHARPR regulatory activity score for base position 62 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_063
Published SHARPR regulatory activity score for base position 63 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_064
Published SHARPR regulatory activity score for base position 64 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_065
Published SHARPR regulatory activity score for base position 65 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_066
Published SHARPR regulatory activity score for base position 66 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_067
Published SHARPR regulatory activity score for base position 67 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_068
Published SHARPR regulatory activity score for base position 68 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_069
Published SHARPR regulatory activity score for base position 69 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_070
Published SHARPR regulatory activity score for base position 70 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_071
Published SHARPR regulatory activity score for base position 71 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_072
Published SHARPR regulatory activity score for base position 72 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_073
Published SHARPR regulatory activity score for base position 73 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_074
Published SHARPR regulatory activity score for base position 74 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_075
Published SHARPR regulatory activity score for base position 75 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_076
Published SHARPR regulatory activity score for base position 76 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_077
Published SHARPR regulatory activity score for base position 77 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_078
Published SHARPR regulatory activity score for base position 78 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_079
Published SHARPR regulatory activity score for base position 79 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_080
Published SHARPR regulatory activity score for base position 80 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_081
Published SHARPR regulatory activity score for base position 81 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_082
Published SHARPR regulatory activity score for base position 82 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_083
Published SHARPR regulatory activity score for base position 83 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_084
Published SHARPR regulatory activity score for base position 84 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_085
Published SHARPR regulatory activity score for base position 85 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_086
Published SHARPR regulatory activity score for base position 86 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_087
Published SHARPR regulatory activity score for base position 87 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_088
Published SHARPR regulatory activity score for base position 88 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_089
Published SHARPR regulatory activity score for base position 89 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_090
Published SHARPR regulatory activity score for base position 90 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_091
Published SHARPR regulatory activity score for base position 91 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_092
Published SHARPR regulatory activity score for base position 92 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_093
Published SHARPR regulatory activity score for base position 93 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_094
Published SHARPR regulatory activity score for base position 94 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_095
Published SHARPR regulatory activity score for base position 95 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_096
Published SHARPR regulatory activity score for base position 96 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_097
Published SHARPR regulatory activity score for base position 97 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_098
Published SHARPR regulatory activity score for base position 98 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_099
Published SHARPR regulatory activity score for base position 99 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_100
Published SHARPR regulatory activity score for base position 100 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_101
Published SHARPR regulatory activity score for base position 101 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_102
Published SHARPR regulatory activity score for base position 102 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_103
Published SHARPR regulatory activity score for base position 103 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_104
Published SHARPR regulatory activity score for base position 104 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_105
Published SHARPR regulatory activity score for base position 105 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_106
Published SHARPR regulatory activity score for base position 106 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_107
Published SHARPR regulatory activity score for base position 107 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_108
Published SHARPR regulatory activity score for base position 108 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_109
Published SHARPR regulatory activity score for base position 109 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_110
Published SHARPR regulatory activity score for base position 110 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_111
Published SHARPR regulatory activity score for base position 111 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_112
Published SHARPR regulatory activity score for base position 112 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_113
Published SHARPR regulatory activity score for base position 113 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_114
Published SHARPR regulatory activity score for base position 114 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_115
Published SHARPR regulatory activity score for base position 115 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_116
Published SHARPR regulatory activity score for base position 116 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_117
Published SHARPR regulatory activity score for base position 117 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_118
Published SHARPR regulatory activity score for base position 118 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_119
Published SHARPR regulatory activity score for base position 119 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_120
Published SHARPR regulatory activity score for base position 120 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_121
Published SHARPR regulatory activity score for base position 121 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_122
Published SHARPR regulatory activity score for base position 122 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_123
Published SHARPR regulatory activity score for base position 123 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_124
Published SHARPR regulatory activity score for base position 124 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_125
Published SHARPR regulatory activity score for base position 125 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_126
Published SHARPR regulatory activity score for base position 126 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_127
Published SHARPR regulatory activity score for base position 127 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_128
Published SHARPR regulatory activity score for base position 128 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_129
Published SHARPR regulatory activity score for base position 129 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_130
Published SHARPR regulatory activity score for base position 130 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_131
Published SHARPR regulatory activity score for base position 131 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_132
Published SHARPR regulatory activity score for base position 132 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_133
Published SHARPR regulatory activity score for base position 133 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_134
Published SHARPR regulatory activity score for base position 134 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_135
Published SHARPR regulatory activity score for base position 135 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_136
Published SHARPR regulatory activity score for base position 136 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_137
Published SHARPR regulatory activity score for base position 137 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_138
Published SHARPR regulatory activity score for base position 138 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_139
Published SHARPR regulatory activity score for base position 139 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_140
Published SHARPR regulatory activity score for base position 140 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_141
Published SHARPR regulatory activity score for base position 141 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_142
Published SHARPR regulatory activity score for base position 142 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_143
Published SHARPR regulatory activity score for base position 143 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_144
Published SHARPR regulatory activity score for base position 144 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_145
Published SHARPR regulatory activity score for base position 145 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_146
Published SHARPR regulatory activity score for base position 146 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_147
Published SHARPR regulatory activity score for base position 147 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_148
Published SHARPR regulatory activity score for base position 148 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_149
Published SHARPR regulatory activity score for base position 149 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_150
Published SHARPR regulatory activity score for base position 150 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_151
Published SHARPR regulatory activity score for base position 151 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_152
Published SHARPR regulatory activity score for base position 152 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_153
Published SHARPR regulatory activity score for base position 153 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_154
Published SHARPR regulatory activity score for base position 154 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_155
Published SHARPR regulatory activity score for base position 155 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_156
Published SHARPR regulatory activity score for base position 156 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_157
Published SHARPR regulatory activity score for base position 157 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_158
Published SHARPR regulatory activity score for base position 158 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_159
Published SHARPR regulatory activity score for base position 159 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_160
Published SHARPR regulatory activity score for base position 160 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_161
Published SHARPR regulatory activity score for base position 161 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_162
Published SHARPR regulatory activity score for base position 162 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_163
Published SHARPR regulatory activity score for base position 163 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_164
Published SHARPR regulatory activity score for base position 164 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_165
Published SHARPR regulatory activity score for base position 165 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_166
Published SHARPR regulatory activity score for base position 166 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_167
Published SHARPR regulatory activity score for base position 167 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_168
Published SHARPR regulatory activity score for base position 168 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_169
Published SHARPR regulatory activity score for base position 169 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_170
Published SHARPR regulatory activity score for base position 170 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_171
Published SHARPR regulatory activity score for base position 171 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_172
Published SHARPR regulatory activity score for base position 172 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_173
Published SHARPR regulatory activity score for base position 173 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_174
Published SHARPR regulatory activity score for base position 174 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_175
Published SHARPR regulatory activity score for base position 175 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_176
Published SHARPR regulatory activity score for base position 176 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_177
Published SHARPR regulatory activity score for base position 177 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_178
Published SHARPR regulatory activity score for base position 178 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_179
Published SHARPR regulatory activity score for base position 179 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_180
Published SHARPR regulatory activity score for base position 180 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_181
Published SHARPR regulatory activity score for base position 181 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_182
Published SHARPR regulatory activity score for base position 182 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_183
Published SHARPR regulatory activity score for base position 183 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_184
Published SHARPR regulatory activity score for base position 184 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_185
Published SHARPR regulatory activity score for base position 185 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_186
Published SHARPR regulatory activity score for base position 186 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_187
Published SHARPR regulatory activity score for base position 187 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_188
Published SHARPR regulatory activity score for base position 188 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_189
Published SHARPR regulatory activity score for base position 189 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_190
Published SHARPR regulatory activity score for base position 190 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_191
Published SHARPR regulatory activity score for base position 191 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_192
Published SHARPR regulatory activity score for base position 192 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_193
Published SHARPR regulatory activity score for base position 193 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_194
Published SHARPR regulatory activity score for base position 194 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_195
Published SHARPR regulatory activity score for base position 195 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_196
Published SHARPR regulatory activity score for base position 196 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_197
Published SHARPR regulatory activity score for base position 197 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_198
Published SHARPR regulatory activity score for base position 198 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_199
Published SHARPR regulatory activity score for base position 199 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_200
Published SHARPR regulatory activity score for base position 200 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_201
Published SHARPR regulatory activity score for base position 201 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_202
Published SHARPR regulatory activity score for base position 202 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_203
Published SHARPR regulatory activity score for base position 203 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_204
Published SHARPR regulatory activity score for base position 204 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_205
Published SHARPR regulatory activity score for base position 205 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_206
Published SHARPR regulatory activity score for base position 206 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_207
Published SHARPR regulatory activity score for base position 207 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_208
Published SHARPR regulatory activity score for base position 208 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_209
Published SHARPR regulatory activity score for base position 209 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_210
Published SHARPR regulatory activity score for base position 210 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_211
Published SHARPR regulatory activity score for base position 211 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_212
Published SHARPR regulatory activity score for base position 212 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_213
Published SHARPR regulatory activity score for base position 213 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_214
Published SHARPR regulatory activity score for base position 214 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_215
Published SHARPR regulatory activity score for base position 215 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_216
Published SHARPR regulatory activity score for base position 216 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_217
Published SHARPR regulatory activity score for base position 217 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_218
Published SHARPR regulatory activity score for base position 218 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_219
Published SHARPR regulatory activity score for base position 219 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_220
Published SHARPR regulatory activity score for base position 220 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_221
Published SHARPR regulatory activity score for base position 221 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_222
Published SHARPR regulatory activity score for base position 222 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_223
Published SHARPR regulatory activity score for base position 223 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_224
Published SHARPR regulatory activity score for base position 224 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_225
Published SHARPR regulatory activity score for base position 225 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_226
Published SHARPR regulatory activity score for base position 226 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_227
Published SHARPR regulatory activity score for base position 227 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_228
Published SHARPR regulatory activity score for base position 228 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_229
Published SHARPR regulatory activity score for base position 229 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_230
Published SHARPR regulatory activity score for base position 230 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_231
Published SHARPR regulatory activity score for base position 231 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_232
Published SHARPR regulatory activity score for base position 232 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_233
Published SHARPR regulatory activity score for base position 233 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_234
Published SHARPR regulatory activity score for base position 234 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_235
Published SHARPR regulatory activity score for base position 235 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_236
Published SHARPR regulatory activity score for base position 236 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_237
Published SHARPR regulatory activity score for base position 237 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_238
Published SHARPR regulatory activity score for base position 238 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_239
Published SHARPR regulatory activity score for base position 239 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_240
Published SHARPR regulatory activity score for base position 240 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_241
Published SHARPR regulatory activity score for base position 241 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_242
Published SHARPR regulatory activity score for base position 242 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_243
Published SHARPR regulatory activity score for base position 243 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_244
Published SHARPR regulatory activity score for base position 244 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_245
Published SHARPR regulatory activity score for base position 245 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_246
Published SHARPR regulatory activity score for base position 246 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_247
Published SHARPR regulatory activity score for base position 247 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_248
Published SHARPR regulatory activity score for base position 248 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_249
Published SHARPR regulatory activity score for base position 249 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_250
Published SHARPR regulatory activity score for base position 250 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_251
Published SHARPR regulatory activity score for base position 251 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_252
Published SHARPR regulatory activity score for base position 252 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_253
Published SHARPR regulatory activity score for base position 253 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_254
Published SHARPR regulatory activity score for base position 254 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_255
Published SHARPR regulatory activity score for base position 255 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_256
Published SHARPR regulatory activity score for base position 256 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_257
Published SHARPR regulatory activity score for base position 257 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_258
Published SHARPR regulatory activity score for base position 258 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_259
Published SHARPR regulatory activity score for base position 259 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_260
Published SHARPR regulatory activity score for base position 260 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_261
Published SHARPR regulatory activity score for base position 261 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_262
Published SHARPR regulatory activity score for base position 262 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_263
Published SHARPR regulatory activity score for base position 263 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_264
Published SHARPR regulatory activity score for base position 264 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_265
Published SHARPR regulatory activity score for base position 265 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_266
Published SHARPR regulatory activity score for base position 266 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_267
Published SHARPR regulatory activity score for base position 267 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_268
Published SHARPR regulatory activity score for base position 268 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_269
Published SHARPR regulatory activity score for base position 269 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_270
Published SHARPR regulatory activity score for base position 270 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_271
Published SHARPR regulatory activity score for base position 271 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_272
Published SHARPR regulatory activity score for base position 272 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_273
Published SHARPR regulatory activity score for base position 273 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_274
Published SHARPR regulatory activity score for base position 274 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_275
Published SHARPR regulatory activity score for base position 275 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_276
Published SHARPR regulatory activity score for base position 276 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_277
Published SHARPR regulatory activity score for base position 277 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_278
Published SHARPR regulatory activity score for base position 278 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_279
Published SHARPR regulatory activity score for base position 279 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_280
Published SHARPR regulatory activity score for base position 280 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_281
Published SHARPR regulatory activity score for base position 281 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_282
Published SHARPR regulatory activity score for base position 282 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_283
Published SHARPR regulatory activity score for base position 283 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_284
Published SHARPR regulatory activity score for base position 284 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_285
Published SHARPR regulatory activity score for base position 285 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_286
Published SHARPR regulatory activity score for base position 286 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_287
Published SHARPR regulatory activity score for base position 287 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_288
Published SHARPR regulatory activity score for base position 288 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_289
Published SHARPR regulatory activity score for base position 289 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_290
Published SHARPR regulatory activity score for base position 290 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_291
Published SHARPR regulatory activity score for base position 291 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_292
Published SHARPR regulatory activity score for base position 292 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_293
Published SHARPR regulatory activity score for base position 293 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.
score_294
Published SHARPR regulatory activity score for base position 294 within the 295-bp hg19 region; positive values indicate activating potential and negative values indicate repressive potential.

Quality control

The authors' pipeline added a pseudocount of 1, library-size normalized RNA and DNA, treated original DNA counts <20 as missing, and applied SHARPR inference with low/high variance priors and replicate combination. This package retained only rows with 295 finite published scores and at least one DNA-qualified tile (original plasmid DNA count >=20) in the matching minimal TATA promoter evidence; for combinedP, either promoter qualified. 15661 of 15720 score rows passed this package QC; 59 were excluded. RNA zeros were not independently discarded because the published missingness rule is DNA-based and the count model uses a pseudocount.

Curation notes

The first identifier component in source_selection_cell_type records the cell type used to select the DNase/chromatin-state region, not the assayed cell line. The score archive concatenates ScaleUpDesign1 and ScaleUpDesign2; this package recovers the array design from the hg19 coordinate files. The count archives omit 87 tiles from Design1 and 96 tiles from Design2 because they were not included in synthesis, while the published score files contain all 15,720 region rows. combinedP is a derived analysis track and is labeled as such.

Cite OpenMPRA

Cite the OpenMPRA database. Include your access date because the collection changes over time.

Please also cite the source studies when using their data.