Experiment / E20B8C189Promoter / Core Promoter MPRA

HepG2 binary STARR-seq promoter motif activity

Sequence determinants of human gene regulatory elements

The random N150 promoter–enhancer binary STARR-seq library was assayed in HepG2 cells. This table presents the deposited promoter-motif RNA/input activity effects for the HepG2 condition.

Download processed table (CSV)Raw source data API documentation

Processed tables are specific to each experiment. Column names, units, measurements, and table structure are not standardized across the database. Check this experiment’s column definitions and quality-control notes before comparing or combining data.

Organism: Human
Taxonomy ID: NCBITaxon:9606
Biosample: CVCL:0027
Reference genome: Not reported / not applicable
Design focus: Synthetic / Motif-focused
Region of interest: Not reported / not applicable

Perturbation & assay details

Basal / Untreated

Episomal binary STARR-seq using random N150 promoter and enhancer sequences in the pCpG-free-promoter–enhancer-SS construct. The processed table is the promoter-side motif activity output from HepG2, with MOODS matching at p=1e-6 and PsiLFC/log2 RNA-over-input effects.

Processed data

50 rows per page. Click a cell to inspect its full value.

Visible columns (8 of 8)

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Filters apply to this table only. The CSV download contains the complete processed table; filtered rows are available through the API.

Column dictionary · 8 definitions

motif_model: Position-frequency-matrix model name
tf: Transcription-factor label associated with the motif model
total_match_count: Total HepG2 RNA motif-match count
input_match_count: HepG2 input-DNA motif-match count
log2_rna_input_effect: HepG2 PsiLFC/log2 RNA-over-input promoter activity effect
effect_direction: Sign-based direction of the activity effect
motif_match_pvalue_threshold: MOODS motif-match p-value threshold used by the source
source_accession: GEO source accession

Quality control

The source file contains 1,121 motif models. Package QC required finite effects, nonnegative integer match counts, and total-plus-input counts of at least 5; all 1,121 rows passed and were retained.

Curation notes

This is the promoter-side aggregate from the binary library, not the deposited GP5d motif-pair interaction table. It does not contain sequence-level alleles.

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