Experiment / E312D2F18Promoter / Core Promoter MPRA

hTERT-RPE1 binary STARR-seq promoter motif activity

Sequence determinants of human gene regulatory elements

The random N150 promoter–enhancer binary STARR-seq library was assayed in hTERT-RPE1 cells. This table presents the deposited promoter-motif RNA/input activity effects for the RPE1 condition.

Processed tables are specific to each experiment. Column names, units, measurements, and table structure are not standardized across the database. Check this experiment’s column definitions and quality-control notes before comparing or combining data.

Perturbation & assay details

Basal / Untreated

Episomal binary STARR-seq using random N150 promoter and enhancer sequences in the pCpG-free-promoter–enhancer-SS construct. The processed table is the promoter-side motif activity output from hTERT-RPE1, with MOODS matching at p=1e-6 and PsiLFC/log2 RNA-over-input effects.

Processed data

50 rows per page. Click a cell to inspect its full value.

Visible columns (8 of 8)
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Filters apply to this table only. The CSV download contains the complete processed table; filtered rows are available through the API.

Column dictionary · 8 definitions
motif_model
Position-frequency-matrix model name
tf
Transcription-factor label associated with the motif model
total_match_count
Total hTERT-RPE1 RNA motif-match count
input_match_count
hTERT-RPE1 input-DNA motif-match count
log2_rna_input_effect
hTERT-RPE1 PsiLFC/log2 RNA-over-input promoter activity effect
effect_direction
Sign-based direction of the activity effect
motif_match_pvalue_threshold
MOODS motif-match p-value threshold used by the source
source_accession
GEO source accession

Quality control

The source file contains 1,121 motif models. Package QC required finite effects, nonnegative integer match counts, and total-plus-input counts of at least 5; all 1,121 rows passed and were retained.

Curation notes

The source uses RPE1 for hTERT-RPE1. This table is the promoter-side aggregate from the binary library and does not contain sequence-level alleles.

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