Experiment / E4TQ53FZ5Sort-Seq / Flow-Seq MPRA

C2C12 MAE-seq 25-bp enhancer catalog

MAE-seq refines regulatory elements across the genome

Supplementary Table S7 provides the final MAE-seq enhancer calls for C2C12 mouse myoblasts as 25-bp genomic coordinates classified as known or novel. The accessible GEO series does not contain a C2C12 per-locus count table, so this experiment packages the genuine MPRA-derived coordinate/classification endpoint available in the supplement.

Processed tables are specific to each experiment. Column names, units, measurements, and table structure are not standardized across the database. Check this experiment’s column definitions and quality-control notes before comparing or combining data.

Perturbation & assay details

Basal / Untreated

The study used the same random 25-bp pMX-mP-mCherry reporter design and fluorescence sorting strategy for its cell-type screens. Supplementary Table S7 is a final coordinate/classification catalog rather than a count matrix: it provides chromosome, start, end, and known/novel class, but no per-element DNA/RNA counts, fold changes, p-values, or q-values. No C2C12 sample or output-count table was present in the accessible GSE193494 series.

Processed data

50 rows per page. Click a cell to inspect its full value.

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Filters apply to this table only. The CSV download contains the complete processed table; filtered rows are available through the API.

Column dictionary · 6 definitions
element_id
Unique mm9 build-and-coordinate identifier for the enhancer element.
chromosome
mm9 chromosome or contig name from Supplementary Table S7.
start
Start coordinate from Supplementary Table S7.
end
End coordinate from Supplementary Table S7; the retained span is inclusive and 25 bp.
length_bp
Element length inferred from the reported coordinates; all retained rows are 25 bp.
enhancer_class
Supplementary classification of the element as known or novel.

Quality control

The authors' Table S7 endpoint was retained only when it had four fields, a valid mm9 chromosome and integer coordinates, an inclusive 25-bp span (end-start+1=25), a known or novel class, and a unique coordinate. All 541,617 rows passed these package-level checks. Because the public C2C12 endpoint contains no per-locus count or significance fields, no effect-size or q-value filtering/imputation was performed.

Curation notes

The abstract reports 541,617 C2C12 enhancers and Supplementary Table S7 contains exactly 541,617 rows. A Results sentence appears to swap the C2C12 and HEK293T counts, but Table S6/S7 and the abstract support the assignment used here. This experiment intentionally preserves the supplement's coordinate/classification endpoint and does not invent activity scores that were not deposited. The biosample is mapped to the canonical C2C12 Cellosaurus record CVCL:0188.

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